BERKELEY - Researchers at the UC Berkeley and the Lawrence Berkeley National Laboratory have put the squeeze — literally — on malignant mammary cells to guide them back into a normal growth pattern.
Shown are fluorescence images of uncompressed (left) and compressed (right) colonies of malignant breast epithelial cells. Compressed colonies are smaller and more organized. (Images courtesy of Fletcher Lab)
The findings, presented Monday, Dec. 17 at the annual meeting of the American Society for Cell Biology in San Francisco, show for the first time that mechanical forces alone can revert and stop the out-of-control growth of cancer cells.